Regions4 is an admitted observer organisation to the UNFCCC process and part of the Local Government and Municipal Authorities (LGMA) Constituency. In this role, Regions4 participates in UNFCCC sessions, meetings, and the annual climate change conferences, and provides input to the process. In addition, Regions4 acts as the co-focal point of the Human Settlements thematic group of the Marrakech Partnership for Global Climate Action. 

As a partner organisation to the UNFCCC Nairobi Work Programme (NWP), Regions4 also shares experiences and knowledge gained through the RegionsAdapt initiative and attends the annual Focal Points Forums of the NWP, opportunities for interaction with country representatives and other stakeholders.